Showing 3 open source projects for "tlcl-19.01.pdf"

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  • 1
    dataMAPPs

    dataMAPPs

    R based pipeline for MHC-associated peptide proteomics (MAPPs) data

    ...dataMAPPs' core is a generic R library that can be tailored to specific projects via dedicated control scripts which also allow reproducible recalculation of results. Consult README file for installation and usage instructions. Further documentation is supplied in PDF format. dataMAPPs is published under GPL license by a team of scientists working for Hoffmann-La Roche AG in Basel, Switzerland. The software is provided as is, to hopefully benefit other researchers. Related Publication in the Journal of Proteome Research: DOI: 10.1021/acs.jproteome.0c00309
    Downloads: 3 This Week
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  • 2

    NOFI ranking

    The Non-Outlier Fragment Ion ranking for enhaced DIA quantification

    ...The outline is as follows: 1) The input contains the list of SWATH fragment ion XICs from the identified and quantified peptides by software tools such as Skyline and OpenSWATH. 2) The first step in NOFI is the computation of the 4 attributes (RTd, FWHMd, IRd and IRrep) used to represent each fragment ion as a vector. 3) Multivariate outlier detection techniques are used to rank all the fragment ions from each peptide. 4) Several figures are generated (a pdf file) to visualize the effect of the Top-N fragment ions over different indicators. 5) The user can choose the number of top fragment ions per peptide, thereby utilizing the optimal subset of high priority Top-N NOFIs for quantification while excluding the impaired fragment ions.
    Downloads: 0 This Week
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  • 3
    CNV Workshop is a web-enabled platform for analyzing genome variation such as copy number variation (CNV). Learn about CNV Workshop in our associated BMC Bioinformatics manuscript: http://www.biomedcentral.com/1471-2105/11/74
    Downloads: 6 This Week
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