Anti-Inflammatory Diet

All health care starts with diet. My recommendations for a healthy diet are here:
Anti-Inflammatory Diet and Lifestyle.
There are over 190 articles on diet, inflammation and disease on this blog
(find topics using search [upper left] or index [lower right]), and
more articles by Prof. Ayers on Suite101 .

Showing posts with label pectin. Show all posts
Showing posts with label pectin. Show all posts

Thursday, January 29, 2015

Healthy Gut Microbiota Means: No Supplements, No Cleanses, No Drugs, No Processed Foods

A healthy, functional gut microbiota (bacteria and fungi) supplies all of the vitamins needed, stimulates the development of a balanced immune system and promotes vitality.  If you feed and maintain the diversity of the pounds of bacteria in your gut, you will be healthy.  If you listen to the medical and food industries, you will be sick, i.e. a good patient/consumer.

Supplements Compensate for Deficiencies/Sickness
The key to this discussion is the functions of the healthy communities of bacteria and fungi called the gut microbiota.  These pounds of bacteria produce all of the vitamins that your body needs, and spiking your diet with multivitamins may disrupt your microbiota, because vitamins are actually the chemical signals used for communications between bacteria in biofilms.  Numerous studies have shown that daily multivitamins are not beneficial, so if you see extra vitamins on the ingredients label, try some whole foods instead.  If, however, you have been exposed to antibiotics or other medications, since most have potent antibiotic activities, then your gut bacteria may not be producing vitamins normally, and you may need to supplement.  Vitamin deficiencies are a symptom of gut dysbiosis, damaged gut microbiota.

Vitamin D is a Steroid Hormone Produced from Cholesterol in Skin by Sunlight
Most people know that sunlight striking skin produces vitamin D, but they still think that they can get a significant amount of vitamin D from their diet.  The confusion comes from the fact that vitamin D is a major hormone that influences many body systems including bone production and immunity.  So in the absence of skin production of vitamin D, the low amounts added to milk are sufficient to prevent deficiency/rickets.  However, chronic inflammation can block solar production of vitamin D, so that even individuals near the equator and basking daily still remain deficient.  Vitamin D deficiency may also, insidiously, be a major source of chronic inflammation.  Thus, most individuals treated for deficiency with supplemental vitamin D3, do not reach high enough levels to suppress chronic inflammation and restart solar production, so they remain deficient.  Chronic inflammation is a symptom of vitamin D deficiency.

Bowel Cleanses Damage Gut Microbiota
The bowels are a long tubelike conveyance and it takes food about a day to travel from table to toilet.  In the colon, all of the plant polysaccharide fibers remaining after removal of sugar, starch, fat and protein, are digested by enzymes of the microbiota and converted into more bacteria and short chain fatty acids that feed the colon tissue. There is nothing toxic left behind in the colon. Protein from meat is readily digested in the stomach and the first part of the small intestines.  Plant materials cannot be digested without the help of a complex array of hundreds of enzymes produced by gut bacteria.  Food intolerances are caused by the loss of particular bacterial species needed for complete digestion of one type of plant fiber.  The bacteria form the stools, and insufficient healthy bowel bacteria, normally fed by the fiber, is the cause of constipation.  Clearly, flushing out bacteria with a "cleanse" is unhealthy and counterproductive.  There is nothing in the colon but gut bacteria and fiber to feed the bacteria. Those bacteria are needed for vitamin production, normal development of the immune system and normal stools.  A cleanse merely removes healthy gut bacteria and leads to constipation or replacement by pathogens. 

Processing Removes Prebiotic Fiber from Food and Starves Gut Microbiota
Diverse and complex plant polysaccharides, e.g. pectin, arabinogalactan, various glucans and fructans, are systematically digested by hundreds of different bacterial enzymes of the healthy gut microbiota.  The sugars that result are eventually converted into short chain fatty acids, such as butyrate, that feed the cells lining the colon.  The plant polysaccharides that feed gut bacteria are called prebiotics.  Unfortunately, prebiotics are removed during food processing to enhance ease of preparation and palatability.  The result of decreased dietary prebiotics is selective starvation and removal of bacterial species needed for the development of the immune system, and autoimmune diseases.

Most Medicines Have Substantial Antibiotic Activity and Damage Gut Microbiota
It is not surprising that antibiotics damage the bacteria in the gut.  What most people don’t realize is that most pharmaceuticals/medicines are developed from the natural antibiotics of plants, phytoalexins.  Numerous recent studies have demonstrated most common medicines, e.g. statins, NSAID, antidepressants, etc. have substantial antibiotic activity and damage gut bacteria.  Surgeons commonly suggest that patients eat yogurt to help repair their gut micro biomes after operations and antibiotics, but they don’t tell them how to fix their gut and immune system as they take medications for the rest of their lives.  The permanently damaged gut just causes further deterioration of the immune system and health.

Damaged Gut Microbiotas/Immune Systems Can Be Fixed
I have several other posts on repair of gut microbiota.


Examination of antimicrobial activity of selected non-antibiotic medicinal preparations.
Kruszewska H1, Zareba T, Tyski S.   Acta Pol Pharm. 2012.  69(6):1368-71.

Wednesday, June 29, 2011

Soluble Fiber: Food for Gut Flora

The human body only produces enzymes to digest proteins, fats, starch and a few simple sugars. The remaining components of food either pass through the intestines undigested (insoluble fiber) or are digested by bacteria and fungi in the colon (soluble fiber.) Soluble fiber feeds gut flora. Insoluble fiber is usually minimized by traditional food preparation, for example grains, because it contains unhealthy materials, such as phytic acid. Soluble fiber is healthy and required for normal development of the gut/immune system, whereas insoluble fiber should be avoided.

Soluble Fibers in Vegetables are Carbohydrates/Polysaccharides

Plant cells are surrounded by cell walls composed of long chains of sugars, polysaccharides. These wall polysaccharides, e.g. pectin, arabinogalactans, xyloglucans, and storage glucans and fructans, are highly complex in structure and can only be digested down to simple sugars by the action of dozens of different enzymes produced by dozens of different bacterial species in the colon. Many plants (as well as fungi and bacteria) also produce unique polysaccharides that are only susceptible to additional unique bacteria enzymes. Thus, digestion of diverse vegetables requires hundreds of different species of bacteria in the gut. Healthy gut flora consists of more than 150 different species of bacteria, which were eaten with food and adapt to the gut environment.

Food Intolerances/Most Food "Allergies"/Constipation Reveal Missing Enzymes

Enzymatic treatment of complex polysaccharides in the gut is a complex process that also yields many intermediate products that can influence both gut flora and the gut itself. A well adapted gut flora can systematically digest most of the food molecules that pass into the colon and produce only short chain fatty acids (CFAs) that feed the colon and pass through the liver to the rest of the body.

Antibiotics or a history of limited food choices and excessive hygiene can result in a simplified gut flora that only partially digests soluble fiber and results in accumulation of unusual byproducts that irritate the gut, and cause bloating and gas. Adverse reactions are called food intolerances or food allergies. Since bowel stools are composed predominantly of loosely packed gut flora, inability to fully digest and convert soluble fiber into more gut flora, also results in constipation.

Soluble Fiber in Meat is also Polysaccharide

Meat is made of fibers of protein connected to bone by polysaccharides. The tendons, gristle and other chewy parts of meat are made of chondroitin sulfate and other glycosaminoglycans (GAGs). Heparin is another GAG, which is released onto the surface of the intestines to block the adhesion of viruses and pathogens to the gut, and is subsequently digested by colon bacteria. Other components of meat (and vegetables), such as nucleic acids and some fats are also digested by enzymes of the gut flora. The versatility of gut flora to adapt to a huge variety of foods permits people to live on very diverse diets, ranging from vegan to paleo.

Modern Diets Starve and Simplify Gut Flora

Modern diets consist of processed foods that are made of fat, protein and starch, all of which are digested and absorbed before reaching the colon. These simplified foods produce a simplified gut flora that may also produce more CFAs rather than stool forming gut bacteria. In other words, eating larger amounts of simpler foods can result in more of the nutrients being absorbed and making it easier to gain weight on less food with a tendency toward constipation. These diets may also select for bacteria that maintain the simplified, "efficient" gut flora community and provide the potential for the spread of obesity through a population. Having friends and relatives who are obese and presumably have gut bacteria that favor obesity, increases the risk of obesity. It seems likely that obesity is contagious.

Simplified Gut Flora also Means a Compromised Immune System

Complexity in the gut flora is also needed to produce a healthy immune system, because different species of bacteria in the gut stimulate the development of different parts of the immune system, which develop in the lining of the gut. Soluble fiber is the normal food for the colon bacteria that control the part of the immune system that regulates autoimmunity and allergy, for example. Obesity is also associated with increased risk of degenerative and autoimmune diseases, which is consistent with defects in the gut flora that reside in the colon. Thus, the modern high carb diet contributes to the symptoms of obesity by elevating blood sugar, blood CFAs, as well as compromising the gut flora needed for normal functioning of the immune system.

Healthy Gut Flora = Anti-Inflammatory Diet + Eating New Bacteria

A damaged or simplified gut flora can be fixed by eating foods that supply nutrients for the body as well as feeding the gut flora, e.g. plenty of different types of soluble fiber. It is also necessary to eat the missing bacteria. Just adding a few probiotics with yogurt will not fix the problem and cooking kills all of the good bacteria. Fermented foods, especially those based on bacteria from your own home and garden, are good sources of health-providing bacteria. Raw vegetables will also provide bacteria that may be useful in your gut flora, as long as the vegetables are not too thoroughly washed. Sterilizing and cooking vegetables may avoid rare pathogens, but will certainly prevent contributions to a healthy gut flora.