Open Source Object Pascal Medical Software for Linux

MCX is a GPU-accelerated, general-purpose, physically-accurate and feature-rich 3-D light transport simulator. It is one of the fastest simulators because it can use tens of thousands of GPU threads to simulate photons in parallel.

SimulAdren is a simulation program for the hypothalamus-pituitary-adrenal axis (HPA feedback control). It is based on a nonlinear MiMe-NoCoDI model and uses the CyberUnits Bricks class library.

Census is a comprehensive cross-platform project manager and integration hub for NONMEM, the gold standard tool for model-based pharmacometric data analysis.

SimThyr is a continuous simulation program for the human pituitary-thyroid feedback control system. Applications of this program cover research, including development of hypotheses, and education of students in biology and medicine, nurses and patients.

SPINA is software for the rapid, reliable and accurate determination of constant structure parameters of endocrine feedback control systems. It is a class of static function tests that require nothing more than steady-state concentrations of hormones or metabolites obtained in vivo. The first version of this cybernetic approach had been developed for the evaluation of the functional status of the thyroid gland, i.e. thyroid's secretory capacity (gain of thyroid, GT or SPINA-GT) and sum activity of peripheral deiodinases (GD or SPINA-GD). A second version has been established for insulin-glucose homeostasis. It delivers the secretory capacity of pancreatic beta cells (SPINA-GBeta), an estimate for the insulin receptor amplification (SPINA-GR) and a static disposition index as a measure for the loop gain of the feedback loop (SPINA-DI). Both implementations of SPINA have been validated in more than 50 clinical studies based on large cohorts.

SimulaBeta is a simulation program for insulin-glucose feedback control. It is based on a nonlinear MiMe-NoCoDI model.

BMI Wizard calculates the body mass index (BMI) from weight and size and vice versa.

Calculator software helping to determine L-T4 and L-T3 substitution dosage according to the algorithms provided by the European Thyroid Association (ETA).

cy.prus is a cross platform simulation environment for medical cybernetics and systems biology. Its purpose is to provide both a facility for simulating life and a GUI for easily constructing biological information processing structures based on XML.