Compare the Top ELN Software as of February 2026

What is ELN Software?

Electronic lab notebook (ELN) software provides researchers with the tools to optimize data collection and storage, transcription processes, information placement, and analysis operations. Compare and read user reviews of the best ELN software currently available using the table below. This list is updated regularly.

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    SciSure

    SciSure

    SciSure

    SciSure is dedicated to transforming laboratories worldwide with innovative digital solutions. We offer a comprehensive Digital Lab Platform (DLP), which integrates the Electronic Lab Notebook (ELN), Laboratory Information Management Systems (LIMS), machine learning, and AI. Our platform is designed to seamlessly integrate with your lab’s equipment and software, offering flexibility, security, and exceptional efficiency. By centralizing and optimizing all your research and process development workflows in a compliant environment, we empower researchers to focus on making ground-breaking discoveries. Our team of lab digitalization specialists is here to support you throughout your digitalization journey. 

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  • 2
    Lockbox LIMS

    Lockbox LIMS

    Third Wave Analytics

    A sample tracking, test result capture, and inventory management cloud LIMS for life science research, biotech/NGS, and industrial QC labs. Includes regulatory support for CLIA, HIPAA, Part 11, and ISO 17025. Nothing is more critical to a lab’s success than the quality, security, and traceability of samples. The Lockbox LIMS system provides robust sample management functionality to laboratory professionals, giving them full visibility on every aspect of a sample’s journey, from accessioning to long-term storage. LIMS analysis is about more than just tracking results- Lockbox’s multi-layered sample storage and location management functionality allows you to define your lab’s storage framework using a variety of location options: rooms, storage units, shelves, racks, boxes, and positions.
    Starting Price: $175/user/month
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  • 3
    Sapio Sciences

    Sapio Sciences

    Sapio Sciences

    Sapio Sciences delivers the Sapio Platform, an agentic AI lab informatics platform that makes life in the lab easier and more productive for scientists. The unified, configurable, low code and scalable environment brings together Sapio LIMS, the market’s most advanced and flexible LIMS for automating research, diagnostics and manufacturing, Sapio ELaiN, the third generation AI lab notebook and scientific co scientist, and Sapio Scientific Data Cloud, the scientific data unification solution with built in organization, search, charting, tools and AI. Biopharma R&D, biotech, CRO and clinical diagnostics organizations use Sapio to run complex workflows and keep samples, experiments and data connected in one place instead of juggling disconnected systems.
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    Labguru

    Labguru

    Cenevo

    Labguru is a secure, cloud-based Electronic Lab Notebook (ELN), LIMS and informatics platform which offers a complete solution for life science research and industry. It records and manages laboratory data and inventory, includes molecular biology tools and chemistry tools, enables automation of the lab, insight into lab data making labs run more efficiently. With Labguru, scientists can design experiments and workflows, capture structured and unstructured data, manage projects, and share their work. Customizable experiment templates, integration of protocols, SOPs, and other cutting-edge features help to increase data quality, streamline workflows and reduce costs. Labguru is available on desktops and mobile devices via the cloud. Labguru is part of Holtzbrinck Publishing Group and serves over 100,000 scientists worldwide from startups, universities, research institutes up to some of the largest pharma companies.
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    LIMSey

    LIMSey

    LIMSey

    LIMSey is a web-based software designed to help engineering and mechanical test labs manage their entire process within one system. Assign and schedule resources, track job progress, manage ever-changing priorities, generate custom test reports, support regulatory audits and accreditation, manage equipment, maintenance, calibrations, training records, and more. All features, updates, and support are always included with no additional modules to buy. We focus on continuous improvement and regularly meet with our existing customers to plan and discuss new features. This collaboration helps drive the development of LIMSey to solve more and more real world problems faced by test labs. Most of our new features come directly from customer requests/. We're also very familiar with ISO / IEC 17025 and would love to help with your initial accreditation or renewal. Call us today at 512-537-9323 for a demo or free trial and start managing your entire lab from one place.
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    SciNote

    SciNote

    SciNote

    SciNote is a cloud-based electronic lab notebook (ELN) with built-in inventory, compliance, & team management tools. It is trusted by the FDA, USDA, European Commission, and 100K+ scientists in over 100 countries. Each premium plan comes with top-rated customer support, and a customer success manager who will work closely with you to ensure successful onboarding and implementation. SciNote provides a top-rated set of data management functionalities, such as inventory tracking & management, protocol & SOP management, compliance (CFR 21 part 11 & GxP), team management & collaboration, integrations and API, project management, safety & security of data and more. SciNote is based in Middleton, WI, USA, with offices in Europe.
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    Sapio LIMS

    Sapio LIMS

    Sapio Sciences

    Sapio Sciences delivers the Sapio Platform, an agentic AI lab informatics platform that makes life in the lab easier and more productive for scientists. The unified, configurable, low code and scalable environment brings together Sapio LIMS, the market’s most advanced and flexible LIMS for automating research, diagnostics and manufacturing, Sapio ELaiN, the third generation AI lab notebook and scientific co scientist, and Sapio Scientific Data Cloud, the scientific data unification solution with built in organization, search, charting, tools and AI. Biopharma R&D, biotech, CRO and clinical diagnostics organizations use Sapio to run complex workflows and keep samples, experiments and data connected in one place instead of juggling disconnected systems.
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    Scilligence ELN

    Scilligence ELN

    Scilligence

    Scilligence ELN is a unified informatics platform that supports R&D effort across all scientific branches focusing on small molecules, mRNA, ADCs, DEL, and more. Our ELN provides an elegant solution to macromolecule work by leveraging the most advanced HELM implementations. With its purposeful design the Scilligence ELN is a platform that will help your lab elevate internal and external collaborative processes. Major Features • Large selection of user-vetted experiment templates • Proprietary indexing capabilities enable structure, HELM, and biosequence queries • Seamless integration with registration, inventory, and assay data warehouse • Proprietary informatics engine enables advanced HELM functionality and enhanced stereochemistry • Auto-extract information from flat files via our Data Reader technology for efficient data capturing and processing
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    Xybion LIMS
    Xybion LIMS (formerly Labwise XD) is an all-inclusive LIMS, ELN, QMS, and DMS. Xybion LIMS drives lab workflows, instills consistency, improves data quality, and supports regulatory compliance with a complete laboratory management solution that connects with your operating systems with powerful laboratory information management and analytics. Xybion LIMS creates optimized workflows for the unique business needs of all regulated laboratories including research, diagnostics, quality control, stability studies, and more.
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    RSpace

    RSpace

    RSpace

    Researchers need tools that enable effective capture, management and sharing of research data. These tools, moreover, must integrate with data storage platforms/applications, other research tools, from enterprise chat to domain-specific tools like protocols.io, and data repositories. RSpace, the Connected electronic notebook, is the only ELN designed to fit seamlessly into the research data infrastructure at modern research-driven universities. As an early stage biotech you need to make rapid progress towards your next milestone. You also need to capture and organize your research data to lay the foundation for longer term IP protection and effective presentation of results to collaborators and investors. RSpace connects with research tools and with other components of the research infrastructure, to ensure the data that researchers produce is not only captured, but also properly managed and eventually made publicly available for others to view, query and re-use.
    Starting Price: $120 per user per year
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    Ansys Cloud Direct
    Access Ansys Cloud Direct anywhere, anytime to obtain endless simulation capabilities compatible with most Ansys solvers. Engineering simulation has long been constrained by fixed computing resources available on a desktop or cluster. Ansys Cloud provides access to on-demand, cloud-based computing resources, including both interactive workstations and HPC clusters, for faster, high-fidelity results offering greater performance insight. Ansys Cloud increases simulation throughput by removing the hardware barrier. Ansys Cloud Direct is a scalable and cost-effective approach to HPC in the cloud. To leverage the combined benefits of cloud computing and best-in-class engineering simulation, Ansys partnered with Microsoft® Azure™ to create a secure cloud solution. Within Ansys Mechanical, Ansys Fluent, Ansys Electronics Desktop, Ansys SPEOS, Ansys Discovery, Ansys LS-Dyna, Ansys LST, Ansys CFX and Ansys Lumerical, you can easily access HPC in the cloud directly from the applications
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    IGOR

    IGOR

    IGOR

    IGOR is a secure, cloud-based Electronic Lab Notebook (ELN)+LIMS platform. It consolidates your research data into a single, searchable location to improve efficiency, ensure data integrity, & enhance accessibility. IGOR features an ELN with integrated digital signatures for review & approval workflows. It standardizes documentation processes, offers comprehensive file & SOP management, & customizable templates, making research documentation well-organized & efficient. IGOR’s inventory can track all your inventory items, including their usage in experiments, relationships to other samples, & storage locations. An integrated mobile app allows users to capture observations or scan hand-written notes for upload to ELN entries. The IGOR workspace is optimized for fast & easy setup, with a user-friendly, ready-to-use framework, customizable to each lab’s workflows. Custom user roles & permissions facilitate secure data sharing & collaboration between internal teams & external partners.
    Starting Price: $30/user/month
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    L7|ESP

    L7|ESP

    L7 Informatics

    L7 Enterprise Science Platform (L7|ESP®) is a unified platform that contextualizes data and eliminates business silos via process orchestration. It's a comprehensive solution that facilitates the digitalization of data and scientific processes in life sciences organizations. L7|ESP has native applications, including L7 LIMS, L7 Notebooks, L7 MES, L7 Scheduling, and more. It can integrate with existing third-party applications, lab instruments, and devices to capture all data in a single data model. It has a low-code/no-code workflow designer and hundreds of pre-built connectors to enable rapid time-to-value and end-to-end automation. By leveraging a single data model, L7|ESP enables advanced bioinformatics, AI, and ML to offer novel scientific and operational insights. L7|ESP addresses data and lab management needs in life sciences, particularly in: ● Research and Diagnostics ● Pharma and CDMO ● Clinical Sample Management Resource Center: l7informatics dot com/resource-center
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    Scispot

    Scispot

    Scispot

    Scispot powers life science labs with a unified LabOS™ platform, combining ELN, LIMS, SDMS, QMS, and AI in one configurable, no-code system. Built for CROs, Molecular Diagnostics, Pathology, Pharma QC, and Drug Discovery, Scispot streamlines sample management, inventory automation, and regulatory compliance. Connect with 200+ lab instruments and thousands of apps to eliminate data silos while maintaining FDA 21 CFR Part 11, GxP, GDPR, and HIPAA compliance. Scispot's AI tools transform experimental data into actionable insights, with flexible workflows that adapt as research evolves—without IT support. Trusted by 1000+ scientists globally, Scispot enables rapid deployment so teams focus on science, not administration. Accelerate discoveries, ensure compliance, and scale operations with a platform purpose-built for modern biotech innovation.
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    Signals Notebook

    Signals Notebook

    Revvity Signals

    Signals Notebook has a modern user interface like the ones on all your personal apps, the need for training is negligible. You will be up and running in no time. That’s part of the reason Signals Notebook is the electronic lab notebook of choice for companies as to whether it’s a team of 4-5 research scientists to the largest biotechs and pharmaceutical companies in the world. Flexibility and breadth to support wide range of workflows now and in the future — including both chemistry, biology, formulations, analytical sciences, and materials sciences. Over 1 million scientists at 4000 organizations count on Signals Notebook to help them streamline their workflows. Structured data capture with APIs and interfaces for integration with instruments, in-house systems, and databases.
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    ScienceDesk

    ScienceDesk

    ScienceDesk

    ScienceDesk data automation demystifies the use of artificial intelligence in materials sciences. A practical tool for your team to add and apply the newest AI algorithms on an everyday basis. Customizable properties, universal identifiers, QR-codes and a powerful textual-numeric search engine that links sample and experimental data. ScienceDesk is an innovative platform for scientists and engineers to interact with, collaborate on and obtain insights into their experimental data. Unfortunately, the potential of this asset is not fully exploited due to the variety of data formats and the strong dependence on experts to manually extract specific information. The ScienceDesk research data management system solves this problem by combining documentation and data analysis in a cleverly-engineered data structure. Researchers and scientists are empowered by our algorithms to gain total control of their data. They can not only share datasets, but even the analysis know-how.
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    Arxspan

    Arxspan

    Arxspan

    Arxspan's Electronic Lab Notebook is a fully integrated cloud platform for scientific data management that combines chemistry and biology data in one system. It is perfectly designed to enhance collaborative research across internal teams & external partners. Support for chemistry and biology experiments and workflows in single cloud ELN. Keyword, advanced, and chemical searching. Attachment and in-line editing for all Microsoft Office, image, and instrument files. Deployment in the private, secure Arxspan Cloud environment eliminates costly hardware acquisition, maintenance and IT overhead. Out of box integration with legacy electronic laboratory notebook systems. View and/or write sharing capabilities at notebook and project level. Configurable user role and permission hierarchies. Experiment signing and witnessing workflows. SAFE BioPharma compatibility for multi-factor capabilities. Support for validation of system and system updates.
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    Dotmatics

    Dotmatics

    Dotmatics

    Dotmatics is the global leader in R&D scientific software that connects science, data, and decision-making. Combining a workflow and data platform with best-of-breed applications, we offer the first true end-to-end solutions for biology, chemistry, formulations, data management, flow cytometry, and more. Trusted by more than 2 million researchers from the world’s leading biopharma, chemicals and materials enterprises, and academic institutions, we are dedicated to working with the scientific community to help make the world a healthier, cleaner and safer place to live. Learn more about our platform and products, including GraphPad Prism, Geneious, SnapGene, Protein Metrics, LabArchives, and more.
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    iVention Lab Execution System (iLES)
    Create seamless data integration and world-class informatics management. iLES is a one-stop communication, documentation, storage and workflow hub for your whole organization, all in real time. iLES has the capabilities of LIMS (Lab Information System), ELN (Electronic Lab Notebook), SDMS (Scientific Data Management System), and DMS (Data Management System). But no matter which digital stage your lab is ready to embark on or which system your lab is ready to replace, iLES uses vendor-neutral technologies to help integrate your islands of data. You will only need to access one system, iLES, to take care of all your lab's needs and communications for all users. Rapid feature release and automated upgrades. Securely access information anywhere in the world using any device with Internet connection. Vendor-neutral technology helps to transform laboratories into tightly integrated paperless environments.
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    IDBS E-WorkBook
    IDBS E-WorkBook is the world’s best-in-class informatics platform for scientific research and discovery. Its flexibility can meet the demands of your industry and those of various business units in your organization today, and can rapidly adapt and scale to meet whatever requirements you may have tomorrow. ELN, LIMS and other legacy software have played an important role in many research projects but their limitations hamper data visibility, obstructs collaboration which hinders further innovations and progress. Combining the very best functionalities of lab-based informatics E-WorkBook goes beyond traditional lab management software, providing cutting-edge data capture and analysis tools, job requesting and management, inventory management, and biology and chemistry functionality. E-WorkBook captures all the information scientists generate and stores it in the cloud. Any system or database used in a lab can be seamlessly ‘plugged in’ or integrated.
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    Agilent SLIMS

    Agilent SLIMS

    Agilent Technologies

    From sample receipt to automated reporting, Agilent SLIMS manages all your samples, experiments, and results. SLIMS combines the best of a laboratory information management system (LIMS) and an electronic laboratory notebook (ELN) to enable end-to-end solutions that allow you to manage the full content and context of your laboratory. No matter how complex your lab, SLIMS can accommodate your needs. Using its intuitive interface, you can efficiently and comprehensively monitor your assets, quickly identify and address errors, and streamline your processes. The system can also be rapidly deployed, saving you time and effort even during setup. Our SLIMS engineers are the real subject matter experts in science and laboratory informatics. They understand your domain and your workflows. They have deployed many solutions for labs across the globe and will assist you during the different phases of the project with installation, validation and adjustment of the software to your needs.
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    E-Notebook

    E-Notebook

    PerkinElmer

    It’s time to make your organization and its scientists more productive with our industry-leading e-notebook, the ideal user-friendly solution for data capturing, archiving, sharing, and protecting intellectual property. With this powerful and intuitive tool, you can drive enhanced collaboration, innovation, and productivity across your organization. Our E-Notebook solution for research and development provides a common workflow that embodies industry best practices for data capture, archiving, and intellectual property while creating a shareable archive to drive collaboration and innovation. There are specialized capabilities for chemistry, biology, formulations, and analytical workflow management, making it the perfect enterprise-wide solution for your organization. With E-Notebook you can more effectively plan, perform, and document experiments to avoid duplication of work and to maximize knowledge gained from experiments.
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    IDBS Polar
    Meet IDBS Polar, the world’s first BioPharma Lifecycle Management (BPLM) platform, eliminating repetitive manual tasks, allowing you to efficiently execute your processes while curating the data you need to accelerate time to market by tackling the biggest challenges in process design, optimization, scale-up, and technology transfer. Interactive data analytics applications, such as bioreactor comparison designed specifically for biopharma development scientists. IDBS Polar is a platform that securely manages drug progression in contexts of workflow, integration, and insight. Workflows designed to simplify the BioPharma Lifecycle with process-aware planning, design, and execution of end-to-end bioprocess and analytical unit operations. Integrations that bring meaning to your data. Rapid integration into your development ecosystem, enabling automation and curating a process-centric data backbone.
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    eLabNotes

    eLabNotes

    Dima Engineering

    eLabNotes™ – A Flexible and Powerful Electronic Lab Notebook eLabNotes™ is an electronic lab notebook (ELNB) that simplifies research workflows for scientists and teams. It offers tools for experiment recording, data management, and collaboration. Designed for scalability and customization, eLabNotes™ improves lab operations, data security, and research reproducibility. Key Features: * Synthesis module with templates, chemistry tools, and analytics integration. * Formulations module for dosage design, BOM setup, and audit trails. * Analytical module for sample management, automated results, and raw data attachment. * Stability management for protocol definition, scheduling, and reminders. * Inventory tracking for materials, equipment, and consumables. * Project monitoring for timelines, budgets, and milestones. * Custom dashboards tailored to roles like scientists and analysts. Get started with eLabNotes™ today and take your research to the next level!
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    Albert

    Albert

    Albert Invent

    Meet Albert, the end-to-end platform that’s digitalizing materials science for the age of AI. From molecular design to industrial production, we've lived the challenges of chemical innovation. Albert is built and implemented by industry veterans to meet the real-world needs of chemists, for today's challenges and tomorrow's innovations. Break down the silos in your R&D processes with Albert’s end-to-end platform. By combining ELN, LIMS, AI/ML, automated SDS generation, and other capabilities, Albert creates a unified flow of knowledge throughout R&D that enables innovation. Equip every scientist in your organization with the power of AI. Albert's specialized AI is trained like a chemist to optimize formulations and accelerate experiments, so you can get new products to market more than 50% faster. Our intuitive design and collaborative implementation, rooted in our own lab experience, ensure seamless integration into your workflows.
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    BIOVIA Notebook

    BIOVIA Notebook

    Dassault Systèmes

    BIOVIA Notebook is a flexible and easy-to-use electronic lab notebook designed to streamline data capture, intellectual property protection, and information sharing for scientific organizations. It offers a high degree of flexibility for electronic data capture, accommodating both small to mid-size companies and large global enterprises. It features a flexible experiment editor that allows users to record experiments quickly and easily, working with text, images, documents, chemical structures, analytical data, and more. Its powerful search functionality enables users to easily store, search, and share entries from any location. BIOVIA Notebook includes built-in e-signatures and workflow reminders to ensure maximum IP protection and regulatory compliance. Access control is managed through versatile permissions based on project and group memberships, allowing configurations to range from open to locked-down as required.
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    BIOVIA ONE Lab

    BIOVIA ONE Lab

    Dassault Systèmes

    BIOVIA ONE Lab is a comprehensive laboratory informatics solution designed to streamline workflows, enhance collaboration, and accelerate research across various scientific domains. It provides a unified environment for managing all laboratory data and processes, enabling scientists to make better decisions faster. ONE Lab is leveraged by companies across multiple industries, including Life Sciences, Consumer Packaged Goods, Energy & Materials, and more. It can be deployed across Research, Development, and QA/QC, with the flexibility to meet the specific needs of scientists in each domain. It manages samples, experiments, data, inventory, equipment, and workflows, integrating with a wide range of laboratory instruments and software to connect existing systems and data seamlessly. ONE Lab removes artificial barriers between ELN, LIMS, LES, equipment integration, and inventory management by employing a single data model across all functional areas.
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    LabLog

    LabLog

    LabLog

    LabLog is designed to be intuitive. Streamlined laboratory data and document management should be about becoming more efficient and precise - not about learning software. Easily record notes, upload files, log samples, and export data trends in one simple ELN platform. Add custom data types to your notes for easy meta analysis and trend reporting. LabLog links all lab documents and information across data points, files and lab samples for more streamlined lab work in collaborative environments. Use barcode printers and scanners to seamless inventory tracking. Reduce collaboration friction and eliminate waste by tapping into LabLog ELN modules designed to make lab work more efficient. From file sharing to e-signatures, LabLog empowers you to give multiple teams in your organization the tools they need to work together more efficiently.
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