Best Endpoint Protection Software in the USA
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Compare the Top Endpoint Protection Software in the USA as of March 2026
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What is Endpoint Protection Software in the USA?
Endpoint protection software is a software platform that provides the solution to secure endpoints—such as laptops, desktops, smartphones, and tablets—against cyber threats and attacks. These platforms provide real-time monitoring and defense mechanisms to protect devices from malware, ransomware, phishing, and other types of threats. Endpoint protection software typically includes antivirus, anti-malware, firewall, encryption, and intrusion prevention features to prevent unauthorized access and ensure data security. It also allows for centralized management, enabling IT teams to enforce security policies, update software, and monitor the health of all devices in the network. By using endpoint protection software, organizations can safeguard their devices and networks from cyber risks while maintaining compliance with security standards. Compare and read user reviews of the best Endpoint Protection software in the USA currently available using the table below. This list is updated regularly.
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1
DriveStrike
DriveStrike
DriveStrike is easy to use, implement and manage. With DriveStrike you can execute secure remote wipe, remote lock, and remote locate commands on any platform. Integrated drive encryption support as well as mobile device management MDM for mobile platforms. Our professional support team is always available to answer your questions and help you install our services or manage your account and devices. Protecting your data and devices has never been easier or more cost effective. If you have questions or need help understanding how best to protect your data please contact us and we will gladly answer your questions. Protect your business with a device and data protection platform that keeps all devices safe with a single solution and Dashboard. Keep your Workstations, MacBooks, iPads, Smartphones, Tablets, Laptops safe, secure, and organized.Starting Price: $0.99 per month -
2
Iru
Iru (formerly Kandji)
Iru (formerly Kandji) is an all-in-one, AI-powered security and compliance platform designed to simplify IT management and strengthen enterprise protection. Built on the Iru Context Model, it unifies identity, endpoint, and compliance into a single intelligent system that understands users, devices, and applications in context. With passwordless workforce identity, advanced endpoint detection, and automated compliance, Iru delivers both security and efficiency without the complexity of multiple tools. Its integrated approach enables IT teams to secure access, prevent threats, and maintain continuous audit readiness—all from one intuitive platform. Trusted by over 5,000 companies including Plaid, Notion, Airbus, and Vercel, Iru transforms how modern businesses manage digital trust. The result is reduced IT workload, improved employee experience, and enterprise-grade protection built for the AI era. -
3
DriveLock
DriveLock
Cyber threats are everywhere, but protecting your IT systems should be as natural as locking your front door. With DriveLock’s HYPERSECURE Platform, safeguarding your endpoints and business data is easier than ever. We integrate the latest security technologies and share our expertise, so you can focus on what matters—without worrying about data protection. Zero Trust Platform takes a proactive approach, eliminating security gaps before they become a risk. By enforcing centralized policies, DriveLock ensures employees and endpoints access only what they need—following the golden rule of cybersecurity: ''never trust, always verify''. -
4
Rippling
Rippling
Stop juggling different tools for identity, access, device, and inventory management. Rippling brings it all together in one seamlessly unified system— deeply integrated and powered by rich employee data. Automate painful, manual tasks like device setup, access provisioning, endpoint management and offboarding in just a few clicks. Get complete visibility across users and hardware, close security gaps before they become risks, and do it all without needing to hire more headcount. It’s the fastest path to scalable, secure IT—without the tool sprawl or overhead.Starting Price: $8 PEPM -
5
SentinelOne Singularity
SentinelOne
One intelligent platform. Unprecedented speed. Infinite scale. Singularity™ enables unfettered visibility, industry-leading detection, and autonomous response. Discover the power of AI-powered, enterprise-wide cybersecurity. The world’s leading enterprises use the Singularity platform to prevent, detect, and respond to cyber attacks at machine-speed, greater scale, and higher accuracy across endpoint, cloud, and identity. SentinelOne delivers cutting-edge security with this platform by offering protection against malware, exploits, and scripts. SentinelOne cloud-based platform has been perfected to be innovative compliant with security industry standards, and high-performance whether the work environment is Windows, Mac or Linux. Thanks to constant updating, threat hunting, and behavior AI, the platform is ready for any threat.Starting Price: $45 per user per year -
6
CrowdStrike Falcon
CrowdStrike
CrowdStrike Falcon is a cloud-native cybersecurity platform that provides advanced protection against a wide range of cyber threats, including malware, ransomware, and sophisticated attacks. It leverages artificial intelligence (AI) and machine learning to detect and respond to threats in real time, offering endpoint protection, threat intelligence, and incident response capabilities. The platform uses a lightweight agent that continuously monitors endpoints for signs of malicious activity, providing visibility and protection without significant impact on system performance. Falcon’s cloud-based architecture ensures fast updates, scalability, and rapid threat response across large, distributed environments. Its comprehensive security features help organizations prevent, detect, and mitigate potential cyber risks, making it a powerful tool for modern enterprise cybersecurity. -
7
SanerNow
SecPod Technologies
SecPod SanerNow is the world's best unified endpoint security & management platform that powers IT/Security Teams automate cyber hygiene practices. It works on an intelligent agent-server model to execute effective endpoint management and security. It gives you accurate vulnerability management with scanning, detection, assessment, prioritization, and remediation capabilities. SanerNow is available on both cloud and on-premise, whose integrated patch management automates patching across all major OSs like Windows, MAC, Linux, and a vast collection of 3rd party software patches. What makes it unique? You can now access other salient features like security compliance management, IT asset management, endpoint management, software deployment, application & device control, and endpoint threat detection and response, all on a single platform. With SanerNow, you can remotely perform and automate these tasks to secure your systems from the emerging wave of cyberattacks.Starting Price: $50/year/device -
8
MyDiamo
Penta Security Systems Inc.
Developed by Penta Security Systems, an APAC leader in encryption technology and web application firewall, MyDiamo is a free open-source database encryption solution, available to all for non-commercial use. The commercial license is available for enterprises and organizations that desire extended features. -
9
UpGuard
UpGuard
The new standard in third-party risk and attack surface management. UpGuard is the best platform for securing your organization’s sensitive data. Our security ratings engine monitors millions of companies and billions of data points every day. Continuously monitor your vendors, automate security questionnaires, and reduce third and fourth-party risk. Monitor your attack surface, prevent data breaches, discover leaked credentials, and protect customer data. Scale your third-party risk program with UpGuard analysts, and let us monitor your organization and vendors for data leaks. UpGuard builds the most powerful and flexible tools for cybersecurity. Whether you’re looking to prevent third-party data breaches, continuously monitor your vendors, or understand your attack surface, UpGuard’s meticulously designed platform, and unmatched functionality helps you protect your most sensitive data. Hundreds of the world’s most data-conscious companies are scaling faster and more securely.Starting Price: $5,249 per year -
10
SafeGuard Cyber
SafeGuard Cyber
SafeGuard Cyber is a SaaS security platform providing cloud-native defense for critical cloud communication applications that organizations are increasingly reliant upon, such as Microsoft Teams, Slack, Zoom, Salesforce, and social media. A blind-spot is growing for security operations as adoption of these tools increases, creating more risk and vulnerability to ransomware, business compromise, and confidential information leakage. Email security lacks the ability to both create visibility outside of email, and primarily defend against malicious files and links. CASB/SASE solutions are difficult to deploy and manage, and the control function is typically left “open” to prevent false positives. Manage day-to-day business communication risk extending beyond email and into enterprise collaboration applications. According to the Verizon DBIR, 92% of social engineering attacks achieve infiltration. -
11
ITsMine Beyond DLP
ITsMine
ITsMine Beyond DLP™ goes beyond traditional Data Loss Prevention (DLP) to protect organizations against all data threats. No policies or endpoint agents needed zero effect on employee productivity, and protection even after data exfiltration. Data loss incidents are becoming more common and more destructive than ever before, whether deliberate or inadvertent or from internal or external factors. Beyond DLP™ is a completely new security approach, that enables organizations to easily track and secure their data wherever it is, within their internal network and beyond. Maintain your high-security standards regardless of whether your data is located in on-prem or cloud-based file systems. Empower employees’ full productivity while controlling the usage and whereabouts of your sensitive data. Hassle-free compliance to data protection regulations, from GDPR, CCPA, PCI to HIPAA, with access control options to sensitive data, data breach detection and clear reporting options. -
12
Sealit
Sealit Technologies
When implementing a Zero Trust security model you shouldn’t question if your accounts or devices will get get compromised - assume they will. With Sealit, the sensitive data in your emails and files will remain fully protected even in that scenario. It takes one click from your existing inbox to encrypt your sensitive emails. It takes one click to encrypt any file format on your desktop. We made sure your workflow isn’t disrupted as we add a strong layer of protection to your sensitive data. Human error accounts for over 90 percent of cyber attacks on businesses, so you need to have a system in place to minimize the risk. Our patent-pending end-to-end encryption ensures each facet of your business is protected. Our app uses biometrics as authentication which provides you a seamless protection experience. Unlike passwords, biometrics cannot be taken away from you, there’s nothing you need to remember, and you always have it with you. -
13
Todyl Security Platform
Todyl
The Todyl Security Platform eliminates the complexity, cost, and challenges of ever-growing security stacks. Manage your security and networking through our cloud-first, single-agent platform. In minutes, you'll be connected and protected, with unmatched visibility and control across your environments. Stop managing products and start building a comprehensive security program. The Todyl Security Platform spans prevention, detection, and response by unifying SASE, Endpoint Security (EDR + NGAV), SIEM, MXDR, and GRC in a cloud-first platform. Todyl streamlines operations simplify architectures and empower your team to deliver highly effective security while simplifying compliance management. Thanks to the global scale and power of the Secure Global Network™ (SGN) Cloud Platform, users can securely connect to company networks, clouds, SaaS apps, and the Internet from everywhere in the world. -
14
Zip Security
Zip Security
No expertise is needed to run a full security program with Zip. Minimize hassle with single-click workflows for everything from account recovery to deploying CrowdStrike. We provide everything you need to execute instantly. Never worry about missing a compliance standard. Monitor your system’s devices, identities, and 3rd party tools at a bird’s eye view and get each metric to where it needs to be. We integrate the best-in-class security tooling like CrowdStrike, Jamf, and Intune to build the enterprise security stack that scales with you, and it’s all behind a single pane of glass. Set consistent security policies across Windows and macOS devices without juggling platform-specific configuration. Zip is your single partner to procure, deploy, configure, and manage your enterprise security program. We’ll manage all of the software you need to buy to meet the standards of your customers, insurers, and compliance regimes. -
15
Rotate
Rotate
Use the Rotate cloud security platform to secure any business with modular hubs and seamless integrations designed to scale your security needs. Gain greater context on cyberattacks and improve remediation by identifying alerts across all hubs, correlating them, and prioritizing incidents by risk level. Synthesize, consolidate, and manage all hubs in Rotate’s XDR. Use your multi-tenancy control center for vulnerability scans and rapid deployments. Manage unlimited clients through a single pane of glass. Empower your business customers with a complete cybersecurity solution and reduce portfolio risk. Rotate protects all types of organizations in the new world of digital-first work. Get complete cybersecurity for every employee who uses email or brings a device to work. Cyber insurance is essential for any organization at risk of a cyber attack, but coverage can be expensive. Comprehensive protection like the type provided by Rotate can help reduce the overall cost of insurance. -
16
ConfigOS
SteelCloud
ConfigOS is currently implemented in classified and unclassified environments, tactical and weapon system programs, disconnected labs, and the commercial cloud. ConfigOS is client-less technology, requiring no software agents. ConfigOS scans endpoint systems and remediates hundreds of STIG controls in under 90 seconds. Automated remediation rollback as well as comprehensive compliance reporting and STIG Viewer Checklist output are provided. ConfigOS was designed to harden every CAT 1/2/3 STIG control around an application baseline in about 60 minutes - typically eliminating weeks or months from the RMF accreditation timeline. ConfigOS addresses Microsoft Windows workstation and server operating systems, SQL Server, IIS, IE, Chrome, and all of the Microsoft Office components. The same instance of ConfigOS addresses Red Hat 5/6/7, SUSE, Ubuntu, and Oracle Linux. ConfigOS content includes over 10,000 STIG and CIS controls. New functionality in Command Center includes a patent-pend -
17
Ivanti
Ivanti
Ivanti offers integrated IT management solutions designed to automate and secure technology across organizations. Their Unified Endpoint Management platform provides intuitive control from a single console to manage any device from any location. Ivanti’s Enterprise Service Management delivers actionable insights to streamline IT operations and improve employee experiences. The company also provides comprehensive network security and exposure management tools to protect assets and prioritize risks effectively. Trusted by over 34,000 customers worldwide, including Conair and City of Seattle, Ivanti supports secure, flexible work environments. Their solutions enable businesses to boost productivity while maintaining strong security and operational visibility.
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