Best Enterprise Medical Billing Software
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Compare the Top Enterprise Medical Billing Software as of March 2026
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What is Enterprise Medical Billing Software?
Medical billing software helps healthcare providers manage the process of billing for medical services, ensuring accurate and timely payments from patients and insurance companies. These platforms typically include features for creating and submitting claims, tracking reimbursements, managing patient records, and ensuring compliance with healthcare regulations such as HIPAA. Medical billing software often integrates with electronic health record (EHR) and practice management systems, streamlining workflows and reducing the risk of errors. By using this software, healthcare providers can improve billing efficiency, reduce administrative costs, and ensure that claims are processed and paid accurately. Compare and read user reviews of the best Enterprise Medical Billing software currently available using the table below. This list is updated regularly.
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1
RXNT
RXNT
RXNT is an ambulatory healthcare technology pioneer that empowers medical practices and healthcare organizations to succeed and scale through innovative, data-backed, AI-powered software. Our fully-integrated, ONC-certified suite of medical software—like Clinical EHRs, Practice Management, Medical Billing and RCM, E-Prescribing, Practice Scheduling, Patient Portal, and more—optimizes clinical outcomes and RCM for your practice. Used by tens of thousands of medical professionals—from large physician practices to medical billing companies—to drive growth, streamline business operations, and improve patient care across all 50 U.S. states. Our unified “Full Suite” system employs a secure, central database so your data passes through every product in real-time from anywhere, and more than 125 million prescriptions have been transmitted and over $7 billion in claims have been processed using RXNT.Starting Price: $118/month -
2
Eldermark
Eldermark Software
Deliver a measurable ROI on workflow process improvements, revenue optimization, marketing and business development, and improved clinical outcomes. Seamlessly connect your entire community, empower your staff to work more efficiently, and generate a holistic view of your community’s financial performance to get the proactive insights you need to streamline your operations and optimize revenue. By centralizing all of your clinical and business operations onto one platform, you’ll give yourself the simplified solutions, economies of scale and enhanced security you need to become a world-class care provider. Gain better insight into your performance against your financial and occupancy goals, improve the safety and satisfaction of your residents and staff, and finally get ahead of the flood of issues you face every day.Starting Price: Contact us -
3
Ensora Mental Health
TheraNest
For solo and small-group mental health practice owners, TheraNest is the EHR and practice-management platform that simplifies clinical documentation, streamlines billing, and empowers sustainable practice growth without administrative headaches. Unlike SimplePractice and TherapyNotes, TherapyNotes uniquely allows therapists to run secure group telehealth sessions (up to 20 participants), automatically insert evidence-based Wiley® treatment plans, and access built-in flat-rate RCM services — all in one place. TheraNest gives therapists back time, control, and confidence by combining workflow automation, AI-enhanced documentation, and reliable U.S.-based support.Starting Price: $29 per month -
4
OpenPM
OpenPractice
Open Practice is pleased to present OpenPM, our cloud-based RCM platform that has propelled the company through 17 consecutive years of double-digit growth. OpenPM connects all the disparate elements of the revenue cycle including; Scheduling & Registration, Billing, Clearinghouse, and Patient Payments/Collections. The result is highly automated accounts receivables management for optimized cash flow, and extensive reporting to help you proactively manage your organization. All of this control is securely hosted and delivered through the browser you already have, providing the perfect combination of security and availability. Medical billing software, revenue cycle management solutions, practice management software, practice management system, medical practice management, EMR integration, EHR integration, practice management scheduling, patient scheduling, online patient billing, patient billing, automatic patient billing and payments, patient payments, electronic patient payments. -
5
AZZLY
AZZLY
AZZLY Rize is the premier clinical and business platform for addiction treatment and mental health organizations. As an all-in-one substance use disorder and mental health specific EHR, Patient Engagement and RCM platform, we serve small, medium, and large clinics. Key features for OUTPATIENT Programs include: scheduling, appointment reminder, Zoom telehealth, treatment plans, progress notes, assessments and surveys. For RESIDENTIAL programs: census, medication management, bed board, withdrawal management, DrFirst e-prescribing, EPCS, PDMP, labs. For all levels of care: alerts, patient engagement portal, electronic billing and claims submission built in. AZZLY Rize empowers your staff through its 5 star training and support services, its simplicity and automation. As a true all-in-one EHR/PM/RCM platform, improved compliance, workflow and accurate billing are achieved real-time. We proudly serve programs in over 33 states and are hosted in Microsoft Azure's private cloud network.Starting Price: $50/user/month -
6
Behave Health
Behave Health
The Behave Health solution combines best-in-class electronic health records software with integrated medical billing & revenue cycle management software. We simplify your operations so you can focus on providing high quality patient care. We support facilities across the behavioral health continuum of care; outpatient, residential, and inpatient. We can support facility providers treating patients with addiction/substance use disorders and mental health disorders. Our solution is perfect for new facilities just starting up or existing facilities looking for a trusted software partner. We know you will love our software so we give you a free trial account to try it out yourself! -
7
NextGen Healthcare EHR
NextGen Healthcare
NextGen Healthcare provides ambulatory practices of all sizes award-winning solutions along with dedicated support and professional services. We align with your goals to achieve the success that results in healthier patients and happier providers. NextGen® Enterprise EHR offers your practice configurable clinical content, intuitive workflows, and an integrated patient experience platform that incorporates telehealth. With NextGen® Mobile, your providers’ smartphones become an extension of your EHR, which saves valuable time. Managed cloud hosting keeps your practice secure and makes upgrades easy, though on-premise options are also available. NextGen® Office is a cloud-based EHR designed to support your practice growth, save staff time, and increase patient volume. This fully integrated clinical and billing platform features specialty-specific EHR content, mobile accessibility, a revenue cycle management system, and a convenient patient portal. -
8
eMedicalPractice
eMedicalPractice
eMedPractice is a cloud-based software system designed to streamline healthcare management functions. Our comprehensive solution begins with the seamless integration of our robust Electronic Health Records (EHR), Practice Management (PM) and Revenue Cycle Management (RCM) modules into one unified platform. This powerful combination of features is just the beginning. We offer a full suite of solutions and services to help you practice with efficiency and optimize workflows. Whether you're a small practice or a large healthcare organization, eMedPractice can help you save time, reduce costs, and enhance patient care. With our clinician-first software, you can manage patient data, automate administrative tasks, and improve revenue generation.Starting Price: $199.00/month -
9
LIS 365
LIS 365
LIS 365 is a laboratory information system (LIS) software system that records, manages, and stores data for clinical & medical laboratories. A best LIS has traditionally been most adept at sending laboratory test orders to lab instruments, tracking those orders, and then recording the results. LIS Software should be used for the automation of workflows for the same purpose for which it is used to automate record keeping. This may not save you effort but it will definitely save you precious time. LIS365 also empowers laboratories to increase their revenues and enhance customer retention. We help them in boosting efficiency, streamline workflows, ensure patient satisfaction and safety. Commonly found functions in a LIS (laboratory information system) are the following, for instance Sample Management, Workflow management, reporting, EHR and ERPStarting Price: $5000.00/one-time/user -
10
PlanStreet
PlanStreet
No matter the size of your organization, our software has everything you need to manage and accelerate your performance. Our secure and scalable case management software has the flexibility to support your client’s needs and empower your agency. HIPAA and HITRUST security standard compliance ensure that your sensitive data and files are secure with PlanStreet. It is time to abandon manual forms and processes. Switch to PlanStreet and automate your client engagement, cases, forms, and files. We’re positive PlanStreet will help you and your team(s) plan, execute, and track work. We are confident that our case management software is the tool your health and human services team needs to get to the next level. Please contact us to schedule a free demo and to learn more about our unique approach to case management.Starting Price: $100/user/month -
11
GreenSense Billing
GreenSense Billing
GreenSense Billing Medical Scheduling tool that simplifies your day conveniently for all your medical scheduling needs. You would never have to worry about your medical billing hassles ever again. Insurance Eligibility Verification Find out about any insurance coverage before the patient makes an appointment. With our eEligibility verification tool you can run queries for individual cases as well as run a batch. Appointment Alerts and Reminders Reduce delays and late arrivals with automated alert reminders. Notify your patients before each appointment to avoid late arrivals and no-shows. Snapshot Your Medical Schedule In the Instant view, you can see the number of your daily medical appointments for each provider and for any particular practice location.Starting Price: 3% -
12
iCareBilling
iCareBilling
iCareBilling is an American Healthcare IT Company that provides Medical Billing, Practice Management, and RCM Software and Services to independent healthcare providers, small, medium, and large medical practices, medical groups, and hospitals throughout the United States. iCareBilling Practice Management Software and RCM Services can be integrated with any EHR/EMR, Practice Management, or Medical Billing Software with any healthcare EDI vendor/clearinghouse in the U.S. healthcare industry. iCareBilling offers integration with all leading EHRs/EMRs in the U.S. Healthcare industry and where EHR/EMR vendor doesn't offer integration, manual workflow is available to take out the patient non-clinical information to submit the claim and receive payments on the behalf of healthcare providers.Starting Price: $450 per month -
13
ReadySetConnect
ReadySetConnect
ReadySetConnect is a practice management software. It is designed to be a complete support tool for clinicians and educators so they can perform their work efficiently and dependably. All patient charts are in one place and can be accessed easily. Users can track and review progress on goals, compare data, collaborate and make timely and effective decisions that help them succeed. This easy-to-set-up software solution is HIPAA-compliant. Unite Your Team: Access ReadySetConnect from any device to meet unique challenges faced by your team and enhance productivity. Effectively Supervise Clinicians And Assistants: In-built workflow enables easy access to review caseloads, schedules, records, and interactions. Collaborate And Gain Confidence With Your Shareholders: Dynamic access rights for your payors and clients to share data in real-time. Make Better-Informed Decisions: Data helps review and analyze each team's performance and inform future planning.Starting Price: Free -
14
MediMobile
MediMobile
We help you reach your goals to reduce costs, deliver improved clinical outcomes, reducing readmission rates, and increase revenue. Grow your revenue with mobile charge capture, clinical documentation, medical billing, and maximizing revenue collection using our cutting-edge technology specially designed for healthcare providers. MediMobile® allows you set up your rounding and appointments in advance or on the fly using your handheld device or any web browser. Set up your rounds and appointments by location, date, room number, name etc. as well as collaborate with other providers within your practice. Customizable to meet your preferences. MediMobile® offers a variety of reporting options to meet the needs of the most novice user or the most advanced number cruncher. MediMobile’s® smart technology integration engine enables real-time integrations with hospital systems, patient management, and billing solutions.Starting Price: Free -
15
Meditab IMS
Meditab Software
Our all-in-one multi-specialty EHR, Practice Management, and Billing software solution allow doctors to deliver the highest quality of care possible to their patients. Streamline your practice's workflows, optimize financial performance, and coordinate quality care faster with IMS. Your practice can’t fully thrive with an inadequate EHR. That’s why Meditab designed its core EHR software, IMS, to do it all. One of the country’s leading EHR software companies, Meditab empowers practices to succeed with innovative technology and one-of-a-kind flexibility. So much more than a typical EMR software, IMS integrates every aspect of your practice into one comprehensive ecosystem. Imagine having an EHR with integrated practice management, medical billing, ICD-10 codes, patient engagement, telemedicine features, and more, you can save time and money while improving your practice efficiency. When your EHR does it all, you can elevate your quality of care and ensure a thriving business.Starting Price: $199.00/month/user -
16
Sehat Central HMIS
Cottonsoil Healthcare Tech
Sehat Central HMIS is a unique, standardized, intelligent, secure, cloud-based platform for healthcare professionals that enables streamlining the practice workflow at Hospitals, Clinics, Labs and Diagnostics Centers. Complete seamless integration of OPD, IPD, Lab, Pharmacy, Radiology departments. We know that most practitioners would love to adopt the new-age technology but are apprehensive of the complex technology that they don't understand fully. We understand these apprehensions of practitioners and hence our efforts are focused on making the solution intuitive that aligns seamlessly with the workflow at your practice. Sehat Central HMIS is a cloud-based, standardized, integrated healthcare platform. It provides a user-friendly interface to enable digitization and automation of end-to-end workflows in clinics and hospitals of all sizes.Starting Price: INR 30,000 -
17
SimplePractice
SimplePractice
SimplePractice is a comprehensive electronic health record (EHR) and practice management software tailored for health and wellness professionals. Serving over 225,000 practitioners, it offers features such as integrated telehealth, customizable documentation templates, billing and insurance tools, and a secure client portal. Designed to streamline administrative tasks, SimplePractice enhances client care and supports the growth of private practices. Starting Price: $35.00/month/user -
18
MedBillit
MedBillit
MedBillit, a cloud-based clinical and billing software, is ideal for hospice agencies. MedBillit assists users in data entry and the automation of workflows to increase the efficiency of the processes. MedBillit key features include nursing assessments, volunteer tracking, compliance alerts, offline forms, and medication recording. With MedBillit, users can automate the claims filling and billing process by its integration with billing to help monitor treatment charges, payor source files, and spent time on patients.Starting Price: $499.00/month -
19
CareVoyant
CareVoyant, Inc.
CareVoyant for Home Care is an integrated enterprise-scale software platform for Home Health Care Agencies offering one or more home-based services – Private Duty Home Care, Private Duty Nursing, Non-Medical, Personal Care, Home and Community Based Services (HCBS), and Home Health - under ONE Patient and ONE Employee, making it a Single System of Record. CareVoyant improves your agency's operational efficiency and bottom line through proactive validations, alerts, and exception-based management. CareVoyant functions - Intake, Authorization, Scheduling, Clinical, Financial, Care Coordination, Reports and Dashboards – improve operational efficiency and bottom line of your home health care agency by eliminating duplicate data entry, streamlining workflow, improving quality of care, and optimizing reimbursement. CareVoyant CV Mobile is an easy to use and integrated platform to meet disparate EVV requirements for multiple states with a standard interface to state aggregators.Starting Price: $500 / month -
20
PracticeSuite
PracticeSuite
PracticeSuite is a practice management, electronic health records (EHR) and patient management solution that is suitable for several medical practices and third-party medical billing companies. PracticeSuite features include patient outreach, scheduling capabilities, patient kiosks, and patient portals. With PracticeSuite's EHR feature, clinical teams can manage clinical measures, include flexible charting tools, and health maintenance. PracticeSuite's EHR also has nationwide connectivity to pharmacies, labs, HIE networks, and the patient portal.Starting Price: 34.95/month -
21
Bridge
BridgeInteract
Bridge delivers patient engagement technology designed with digital empathy to restore the human connection in healthcare while reducing friction for patients, physicians, and staff. Its unified platform brings together access, communication, intake, scheduling, and payments into a single, seamless digital experience that works inside the EHR. Unlike competitors that rely on autonomous automation, we prioritize the provider-patient relationship. We ensure technology supports the compassionate care provided by your staff, rather than erecting a barrier of bots between the patient and provider. By eliminating fragmented tools and unnecessary administrative work, Bridge helps care teams spend less time managing systems and more time focusing on patients. The result is a simpler, more intuitive experience that patients actually use, staff can manage with ease, and physicians trust — driving a measurable return on experience and efficiency across your organization.Starting Price: $500.00/month -
22
Ensora ABA Suite
Ensora Health
Purposefully designed by BCBAs, Ensora ABA Therapy (formerly WebABA) simplifies your daily operations, making practice management a breeze. Optimize schedules based on staff credentials and insurance limits, send automated reminders to reduce no-shows, and process claims faster with integrated documentation. It also includes features like mobile access, HIPAA-compliant document management, and customizable reporting, making it easier for ABA providers to improve operational efficiency and focus on delivering high-quality care.Starting Price: $27/client/month -
23
MDBilling.ca
MDBilling.ca
MDBilling.ca is a secure, online medical billing software. It is the only billing software with Clinical Logic that uses an advanced rule-based engine to help you optimize claims to prevent rejections and maximize your revenue.Starting Price: $0.01/month/user -
24
Aarogya
Dataman Computer Systems
Aarogya, Hospital Management Information System, offers features such as OPD Management, IPD Management. OT Management, TPA Management, Pathology Lab Management, Inventory Management, Finance & Accounting Management, Blood Bank Management and more. It offers business hours, and 24/7 live support. Reliable software solution for mid-size to large hospitals, Investigations labs and polyclinics.Starting Price: $5000 -
25
Feegow
Feegow
More intelligence for your calls and savings for you. No more paper and losing information. Here, everything is integrated and secure 100% in the Cloud. There are 7 types of agenda to meet all realities. Your clinic working the way that best fits your routine and without missing any time! The most powerful on the market! Robust, he meets every particularity that your clinic has. From the simplest to the most complex features, all in one place. Monitoring and administration so you don't come across any waste! Resources for relationship with agreements and control of glosses with agility and efficiency. 360° management at a click! Clarity and security for you to monitor all data in a complete Report Center with full control of the business. Total organization for your stock integrated with the other modules. You avoid discards, keep the necessary quantities and don't lose any more money!Starting Price: $19.21 per user per month -
26
Transcure
Transcure
Transcure is a healthcare IT company offering EHR solutions and medical billing services to practices in the USA. We offer advanced EHR solutions, medical billing solutions and practice management making healthcare practices thrive. Our products and services help providers to ensure effective practice management and improve revenue cycle management. Embark on a transformative journey with Transcure, where innovation converges with excellence in healthcare IT solutions. Established in 2002, we have proudly stood at the forefront of providing comprehensive Revenue Cycle Management (RCM) solutions in the USA. We are dedicated to empowering hospitals, group practices, and solo practices. We have grown to a team of +1100 highly qualified billers and coders strategically headquartered in Woodbridge, New Jersey, and Dallas, Texas. Our customized approach ensures providers achieve a strong revenue cycle process with timely reimbursements in the healthcare industry.Starting Price: 5k$ -
27
pMD
pMD
End-to-end practice management and revenue cycle solutions. From patient intake to getting paid, pMD has all the software and services you need to run your medical practice. With fewer systems involved, there's less room for errors and inefficiencies. Use all of the features pMD has to offer, or we can integrate seamlessly with your existing systems. A comprehensive and secure communication strategy means fewer gaps in care and a better patient experience. Delivering the best possible care means having a standardized communication channel to connect about and with your patients. We make sure all the important patient information is accessible in one place, saving you valuable time when you need to access it. pMD offers the comprehensive, integrated, and HIPAA-compliant telemedicine platform solution health care providers need to provide unparalleled patient care. Explore all the easy-to-use telehealth software app offers and get pMD telemedicine for your practice and patients.Starting Price: Free -
28
Oryx
Oryx
Oryx is a cloud-based dental practice management software designed to streamline various aspects of dental operations, including billing, imaging, patient communication, and data security. It offers features such as data-driven billing and practice management, advanced imaging and charting tools, efficient patient scheduling and communication, robust data security measures ensuring HIPAA compliance, and comprehensive revenue cycle management services. Oryx serves a diverse clientele, including independent practices, multi-location dental service organizations, specialists, pediatric dentists, and Canadian dental professionals. It emphasizes modern, tech-enabled solutions to enhance patient experiences and practice efficiency, with transparent pricing that can result in significant savings compared to other dental software options. Starting Price: Free -
29
Enable Healthcare
Enable Healthcare
Enable Healthcare’s Electronic Health Records (EHR) is an AI‑powered clinical solution that accommodates solo practices through large multispecialty groups by unifying robust documentation, administrative workflows, and patient engagement in a single interface. It visualizes interactive clinical data to inform decisions for individual patients and entire populations, while its real‑time dictation app eliminates manual typing with accurate voice recognition. Built on HPI‑based algorithms, the intelligent coding engine automates code detection, integrates payer‑specific codes, and issues care‑gap alerts to optimize revenue integrity. With enableAssist, clinicians leverage AI‑driven charting prompts to generate assessment and plan narratives instantly, and eApredict computes and displays color‑coded patient risk levels. Integrated telehealth capabilities facilitate virtual visits and simplified transition‑of‑care reviews.Starting Price: $500 per month -
30
DocVilla
PS3G
DocVilla is a comprehensive, multi-specialty, mobile-friendly, HIPAA-compliant cloud-based health technology platform that integrates EHR/EMR, telehealth, e-prescribing, patient engagement, medical billing, analytics and reporting, direct primary care, inventory management, remote patient monitoring, and more into a unified, configurable suite. Providers simply sign in to access a customizable electronic medical records system with secure messaging, video visits, controlled-substance e-Rx, and a free patient portal for scheduling, payment, and secure communications. The platform streamlines workflows by automating eligibility checks, claim submissions, charge posting, insurance eligibility and claim filing, ERAs/EOBs, medical dictation and speech-to-text, patient consent forms, lab integrations, electronic fax, and automatic appointment reminders.Starting Price: $100 per month
