Momentum-entangled atom pairs are used to demonstrate quantum non-locality, where changing one atom in an entangled pair instantly alters the state of the other atom. This result paves the way to study interactions between quantum states and gravity.

High-voltage lithium-metal batteries face safety and stability challenges. Here, authors develop a non-flammable triethyl phosphate-based electrolyte using a triple-salt solute strategy to induce a bilayer solid electrolyte interphase, enabling long-term cycling of 4.5 V Li metal batteries.

Deep brain stimulation is effective but invasive. Here, the authors develop an injectable conductive hydrogel that forms in situ and enables wireless neuromodulation under volume conduction via capacitive coupling, showing therapeutic potential in a Parkinson’s disease rat model

Lithium metal offers high specific capacity but suffers from dendrite growth and poor cycling stability. Here, authors develop a 3D Li-Zn-Li3N/CNT composite combining ductile Li-Zn alloy and a mechanically robust Li3N-CNTs network, enabling thin, durable electrodes with uniform lithium deposition, demonstrating a pouch-cell with a specific energy of 553 Wh kg-1.

The direct coactivation of inert hydrocarbons and water typically requires high oxidation potentials. Here, the authors report that a Ni-activated tungsten-oxygen covalency anode is designed to steer the oxygen transfer from water to benzylic C(sp³)–H bonds via Ni-regulated interfacial water structure.

Transportation infrastructure threatens forests, but past studies have been regional or focused on single metrics like forest cover. This global analysis finds road-adjacent forests lose cover, height, and productivity and become more fragmented.

This study finds a record-breaking upstream-downstream zonal-consistent variation in the Eurasian jet axis since 1999, which is enhanced with global warming, and induces a circumglobal Silk Road teleconnection, linking climate extremes across the Northern Hemisphere.

Humans alter the daily timing of animal activity, potentially reshaping predator–prey interactions. This meta-analysis reveals that larger species tend to “lose” under human disturbance, with large predators overlapping less with their prey, and large prey overlapping more with their predators.

Soil-based compound dry-hot extremes represent a critical yet underappreciated driver of ecosystem stress. This study shows that their frequency and coverage area have increased markedly in China due to anthropogenic soil warming, which may pose growing adverse impacts on vegetation productivity.

Global heat stress has increased, with 52% of land area showing rising mean intensity and 67% showing more extreme heat stress days. Anthropogenic climate change dominates these trends and widens inequalities across economies.

The authors in this work present a study with multiplexed gene editing that is used to assess all possible mutations at a native drug binding site. The approach yields data that predicts spontaneous resistance, that aligns with in silico predictions, and that promises to facilitate drug discovery.

T cell activation requires major metabolic adaptation. Here authors find that in mice and humans, expression of the NAD/H-synthesis enzyme nicotinamide riboside kinase 1 (NRK1) increases in CD4+ T cells upon activation, particularly within the cytoplasm, which impacts NADP/H and reactive oxygen species signalling, restraining activation and cytokine production while promoting CD4 + T cell survival during viral and fungal infections.

The structure-function relationship of chromatin fibers remains poorly understood. Here, the authors use a hybrid experimental-computational approach to show that active and inactive genomic loci have different chromatin structures.

Nuclear protein homeostasis relies on proteasome import into the nucleus. Here the authors identify how assembled human proteasomes are transported across the nuclear pore complex and reveal a mechanism enabling the large complex to bypass pore size limitations.

Sensory encoding and memory retrieval are oppositely modulated across the cycle of infra-slow brain dynamics in both humans and mice, revealing a conserved brain mechanism coordinating seconds-scale sensory and mnemonic processing.

This study presents the inhibitory primary auditory cortex – anterior cingulate cortex pathway underlying the auditory-pain crosstalk in mice, thus serving as a neural substrate for music therapy in visceral pain management.

Here, the authors present structural and mechanistic insights into the inhibition of fungal β-1,3-glucan synthase, a key enzyme in fungal cell wall synthesis, by triterpenoid drugs.

Here, in a cross-sectional study of 209 individuals living in communities with contrasting Schistosoma mansoni endemicity in Uganda, the authors identify gut microbiome and metabolome signatures associated with S. mansoni infection and cardiovascular disease risk.

This review calls for integrated Skin NTD action, using One Health to analyze complex human, animal, and environmental transmission. It highlights knowledge gaps and urges expanded, standardized diagnostics and systematic data collection on social/financial barriers for patient-centered control.

Taxanes, including paclitaxel (PTX) and Nab-PTX (comprising PTX bound to albumin nanoparticles), are first-line chemotherapeutic agents in breast cancer therapies. Here, the authors report that PTX, but not Nab-PTX, induces the expansion of tumor-promoting TREM2+ macrophages as a mechanism underlying the inferior antitumor efficacy of PTX compared with Nab-PTX in patients with breast cancer.

The study evaluates using ultra-high-performance fiber-reinforced cementitious composite (UHPFRC) for bridge maintenance in Switzerland, finding it feasible for 99.7% of bridges, potentially saving 7.7 million tons of CO₂ equivalent and 18.5 billion Swiss francs over 80 years compared to traditional methods.

Voluntary deference to prestigious individuals is a unique feature of human social life. Here, the authors show that human prestige psychology can promote marked-yet-adaptive inequalities in influence while remaining non-coercive.

Africa’s public health genomics capacity has expanded substantially since the COVID-19 pandemic; however, workforce development is currently constrained by access, cost and sustainability. In this Perspective, the authors present virtual reality as a strategic tool for sustainable and equitable capacity building in genomics.

High energy use in controlled environment agriculture clouds its potential as a lower-carbon option for agri-food transformations. The authors find that using a Maximum Energy-use Threshold in specific contexts can provide a potential solution.